Douglas K. Rex, MD, MASGE
reviewing Pilonis ND, et al. Gastroenterology 2020 Dec 8.
Many guideline groups endorse offering patients multiple options for colorectal cancer screening, but randomized trials have shown that overall adherence is as high with sequential offers as multiple options, and more patients undergo colonoscopy (or another test offered first) with sequential offers. In this trial comparing participation outcomes, 12,485 patients were randomized to colonoscopy only, a sequential offer of colonoscopy and then fecal immunochemical testing (FIT), or the choice between colonoscopy and FIT.